Subtitle:Modeling theoretical tools to test and evaluate experimental equilibrium effects
Author:Niels Bindslev, MD, Associate Professor and Lecturer in Physiology at the Department of Biomedical Sciences, Faculty of Health Sciences, University of Copenhagen, Denmark
Print ISBN: 978-91-977071-0-7
Electronic ISBN: 978-91-977071-1-4
About this book:Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state.
The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze ones own data.
The author suggests that:
Table of Contents
Senior Publisher at Co-Action Publishing, Anne Bindslev, speaks with the author about the book. See interview here.
natural drugs, industrial drugs, ligand receptor interactions, synergy, pharmacodynamics, combinatorial drug therapy, toxicology, physiological processes, enzymology, molecular biology, plant biology, systems biology, synthetic biology, biological regulation, network analysis, epigenetics, dose-response, allosteric, homotropic, heterotropic, theoretical modeling, one-state models, two-state models, equilibrium, steady-state, dose-response curves, reaction schemes, co-operativity, auto-modulation, auto-inhibition, auto-intervention, receptors, channels, co-transporters, pumps, G protein-coupled receptors (GPCRs), carriers, bell-shaped synagics
pharmacologists, biochemists, enzymologists, molecular biologists, physiologists, plant biologists, toxicologists and other researchers studying systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as medical clinicians interested in drug application and combinatorial drug therapy.
210 x 280 mm
Number of pages:
Number of illustrations:
Ca 260 illustrations of which 140 in colour
The book is supported by the LOCKSS system to ensure a safe and permanent e-archive with the libraries.
© 2008 Niels Bindslev (except for rights associated with commercial use, which reside with Co-Action Publishing).
This is an Open Access book distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. No permission required except for commercial use, distribution, and reproduction.